BRAIN · Vol. 15 · Issue 1 · 2024

From Etiology
to Coping

An interactive academic journey through congenital heart malformation pathways, neural crest development, and parental coping.

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Article information

Etiological Factors and Parental Coping in Congenital Heart Malformations

Ştefana Moisa · Lăcrămioara Butnariu · Carmen Valerica Ripa · Roxana Gabriela Cobzaru · Laura Trandafir

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Etiology Explorer

Select a factor to trace a pathway from cause to mechanism to associated cardiac findings.

CONGENITAL HEART MALFORMATIONS Geneticabnormalities NKX2.5 &modifier genes 22q11.2deletion Retinoic acidimbalance Alcoholexposure Alagillesyndrome Waardenburgsyndrome Noonan /LEOPARD
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Neural Crest Journey

Switch between developmental scenarios and watch the migration field respond.

NEURAL CREST ORIGIN CARDIAC OUTFLOW REGION
NORMAL MIGRATION

Coordinated neural crest migration

Cells follow organized trajectories toward the developing cardiac outflow region.

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The Coping Wheel

A continuously rotating map of coping patterns described across the studies reviewed in the article. Hover or tap a segment to explore it.

PARENTof a child
with CHD

Hover / tap a segment · wheel pauses while you explore